Pain perception in hand osteoarthritis: relation between clinical nodes, radiological severity, pain threshold and brain pain processing
نویسندگان
چکیده
منابع مشابه
Functional MRI demonstrates pain perception in hand osteoarthritis has features of central pain processing.
BACKGROUND Hand osteoarthritis (HOA) is typified by pain and reduced function. We hypothesised that people with HOA have enhanced sensitivity and activation of peripheral nociceptors in the hand, thereby potentiating chronic pain. In our study we aimed to assess if central sensitisation mediates pain perception in osteoarthritis of the hand. METHODS Participants with proximal and distal inter...
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Objectives When pain is assessed in research, it is most commonly assessed using patient-reported outcome measures (PROMS). These measures can provide information about pain severity, distress and qualities, but they are unable to provide information about the underlying mechanisms contributing to pain perception. Quantitative Sensory Testing (QST) comprises non-invasive tests which can identif...
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Though the sensitivity of the patient to noxious stimulation has long been recognized as an important factor in relation to symptom production, its quantitative assessment has received little attention. While it is common for clinicians to express an opinion on the sensitivity of the patient, usually when surprised by an apparent excess or absence of pain, such opinions are almost invariably un...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2012
ISSN: 1063-4584
DOI: 10.1016/j.joca.2012.02.593